Saturday, January 21, 2023

Choline

 Choline

Chemistry and sources

It was first isolated by Stracker in 1849 from body fluids. It is a component of lecithin, sphingomyelin, acetylcholine, etc.

Sources

Butter, nervous tissue, yolk of egg are very rich sources.

Synthesis

It can be easily synthesized in the human body from methionine and ethanolamine.

Functions of choline

1. Lipotropic action- choline prevents the deposition of fats and accelerates the rate of removal of fat from the liver. It accelerates the rate of phospholipid formation and mobilization of fat.

2. Synthetic functions- It takes part in synthesis of Lecithin, Sphyngomyelin and acetylcholine. First two are phospholipids.

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