Saturday, January 21, 2023

Essential fatty acids

 


Essential fatty acids

EFAs (ω-3 and ω-6 fatty acids) are fatty acids that humans and other animals must ingest because the body requires them for good health but cannot synthesize them. The term essential fatty acid refers to fatty acids required for biological processes but does not include the fats that only act as fuel. Only two fatty acids are known to be essential for humans- 

Some other fatty acids are sometimes classified as conditionally essential, meaning that they can become essential under some developmental or disease conditions; examples include 

Sources

Fish and shellfish, seaweed oil, flaxseed (linseed) and flaxseed oil, hemp seed, olive oil, soya oil, canola (rapeseed) oil, chia seeds, pumpkin seeds, sunflower seeds, leafy vegetables, and walnuts.

Daily Requirements

alpha-linolenic acid- omega-3 fatty acid

2 gm

linoleic acid- omega-6 fatty acid

10 gm

 

Functions of essential fatty acids

1. They help in normal growth.

2. They are structural components of cells.

3.they are modified to make the classic Eicosanoids (affecting inflammation and many other cellular functions) the endocannabinoids (affecting mood, behavior and inflammation) , the lipoxins which are a group of eicosanoid derivatives formed via the lipoxygenase pathway from ω-6 EFAs and resolvins from ω-3 (in the presence of acetylsalicylic acid, downregulating inflammation) the  isofurans,  neurofurans, isoprostanes, hepoxilins, epoxyeicosatrienoic acids (EETs) and  neuroprotectin D.

4. They are responsible for the maintenance of normal healthy skin.

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